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Improving Interobserver Variation in Reporting Gadolinium-Enhancing MRI Lesions in Multiple Sclerosis Neurol 49:1682-1688, Barkhof,F.,et al, 1997 See this aricle in Pubmed Article Abstract Gadolinium-enhanced MRI is a sensitive and objective means to monitor disease activity in multiple sclerosis(MS).We evaluated the interobserver agreement and the value of observer training in reporting enhancing lesions from serial MRI.Scans of 16 MS patients were evaluated by five inexperienced and five experienced observers before and after consensus formation and training.In both groups MADM scores were<0.72 for baseline and new lesions but>1.2 for persistent lesions.Interobserver agreement is improved by training,especially in inexperienced readers.Interobserver agreement in reporting gadolinium-enhanced lesions is high which validates the use of serial enhanced MRI as an outcome parameter in treatment trials in MS.

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(click to filter results - removes previous filter) gadolinium interobserver agreement MRI MRI,abnormal MRI,contrast enhanced MRI,serial multiple sclerosis multiple sclerosis,treatment of treatment of neurologic disorder

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